Articles about LAM patients who have taken mTOR inhibitors during pregnancy:

Margoles HR, Gomez-Lobo V, Veis JH, Sherman MJ, Moore J Jr. Successful maternal and fetal outcome in a kidney transplant patient with everolimus exposure throughout pregnancy: a case report. Transplant Proc. 2014 Jan-Feb;46(1):281-3. doi: 10.1016/j.transproceed.2013.09.029. PubMed PMID: 24507068.

Carta P, Caroti L, Zanazzi M. Pregnancy in a kidney transplant patient treated with everolimus. Am J Kidney Dis. 2012 Aug;60(2):329. doi: 10.1053/j.ajkd.2012.05.012. Review. PubMed PMID: 22805522.


Veroux M, Corona D, Veroux P. Pregnancy under everolimus-based immunosuppression. Transpl Int. 2011 Dec;24(12):e115-7. doi: 10.1111/j.1432-2277.2011.01356.x. Epub 2011 Sep 22. PubMed PMID: 21950359.

Faehling M, Wienhausen-Wilke V, Fallscheer S, Trinajstic-Schulz B, Weber J, Leschke M. Long-term stable lung function and second uncomplicated pregnancy on sirolimus in lymphangioleiomyomatosis (LAM). Sarcoidosis Vasc Diffuse Lung Dis.   2015 Sep 14;32(3):259-64. PubMed PMID: 26422572.


Dębska-Ślizień A, Gałgowska J, Chamienia A, Bułło-Piontecka B, Król E,  Lichodziejewska-Niemierko M, Lizakowski S, Renke M, Rutkowski P, Zdrojewski Z, Preis K, Sledziński Z, Rutkowski B. Pregnancy after kidney transplantation: a single-center experience and review of the literature. Transplant Proc. 2014 Oct;46(8):2668-72. doi: 10.1016/j.transproceed.2014.08.015. PubMed PMID: 25380891.


Framarino-dei-Malatesta M, Derme M, Manzia TM, Iaria G, De Luca L, Fazzolari L, Napoli A, Berloco P, Patel T, Orlando G, Tisone G. Impact of mTOR-I on fertility and pregnancy: state of the art and review of the literature. Expert Rev Clin Immunol. 2013 Aug;9(8):781-9. doi: 10.1586/1744666X.2013.824243. Review.  PubMed PMID: 23971756.

 

Recent Scientific Articles

December 2015

Atochina-Vasserman, Elena N., Elena Abramova, Melane L. James, Ryan Rue, Amy Y. Liu, Nathan Tessema Ersumo, Chang-Jiang Guo, Andrew J. Gow, and Vera P. Krymskaya. 2015. “Pharmacological Targeting of VEGFR Signaling with Axitinib Inhibits Tsc2-Null Lesion Growth in the Mouse Model of Lymphangioleiomyomatosis.” American Journal of Physiology. Lung Cellular and Molecular Physiology 309 (12): L1447–54. doi:10.1152/ajplung.00262.2015.

Ferreira Francisco, Flavia Angelica, Arthur Jr Soares Souza, Glaucia Zanetti, and Edson Marchiori. 2015. “Multiple Cystic Lung Disease.” European Respiratory Review : An Official Journal of the European Respiratory Society 24 (138): 552–64. doi:10.1183/16000617.0046-2015.

Kumasaka, Toshio, Yoshito Hoshika, Etsuko Kobayashi, Keiko Mitani, Makiko K. Okura, Young Kwon Hong, Kazuhisa Takahashi, and Kuniaki Seyama. 2015. “A Model of Lymphangioleiomyomatosis in a Three-Dimensional Culture System.” Lymphatic Research and Biology 13 (4): 248–52. doi:10.1089/lrb.2015.0009.

Moir, Lyn M. 2015. “Lymphangioleiomyomatosis: Current Understanding and Potential Treatments.” Pharmacology & Therapeutics, December. doi:10.1016/j.pharmthera.2015.12.008.

Sebaaly, Jamielynn, Laura Bowers, Joe Mazur, Rob Kotloff, Blake R. Olmsted, Allen Kaplan, and Charlie Strange. 2015. “Rapid Oral Desensitization to Sirolimus in a Patient with Lymphangioleiomyomatosis.” The Journal of Allergy and Clinical Immunology. In Practice, December. doi:10.1016/j.jaip.2015.11.007.

 

November 2015

Chebib, N., C. Khouatra, R. Lazor, F. Archer, C. Leroux, D. Gamondes, F. Thivolet-Bejui, J. F. Cordier, and V. Cottin. 2015. “Pulmonary lymphangioleiomyomatosis: From pathogenesis to management.” Revue des maladies respiratoires, November. doi:10.1016/j.rmr.2015.10.005.

Crawford, Todd C., Joshua C. Grimm, J. Trent Magruder, R. Scott Stephens, Christopher M. Sciortino, A. Jason Vaught, Janyne Althaus, Ashish S. Shah, and Bo S. Kim. 2015. “A Curious Case of Acute Respiratory Distress Syndrome.” Journal of Surgical Case Reports 2015 (11). doi:10.1093/jscr/rjv140.

Ferreira Francisco, Flavia Angelica, Arthur Jr Soares Souza, Glaucia Zanetti, and Edson Marchiori. 2015. “Multiple Cystic Lung Disease.” European Respiratory Review : An Official Journal of the European Respiratory Society 24 (138): 552–64. doi:10.1183/16000617.0046-2015.

Fujita, Atsushi, Katsutoshi Ando, Etsuko Kobayashi, Keiko Mitani, Koji Okudera, Mitsuko Nakashima, Satoko Miyatake, et al. 2015. “Detection of Low-Prevalence Somatic TSC2 Mutations in Sporadic Pulmonary Lymphangioleiomyomatosis Tissues by Deep Sequencing.” Human Genetics, November. doi:10.1007/s00439-015-1611-0.

Kumasaka, Toshio, Yoshito Hoshika, Etsuko Kobayashi, Keiko Mitani, Makiko K. Okura, Young Kwon Hong, Kazuhisa Takahashi, and Kuniaki Seyama. 2015. “A Model of Lymphangioleiomyomatosis in a Three-Dimensional Culture System.” Lymphatic Research and Biology, November. doi:10.1089/lrb.2015.0009.

 

October 2015

 

Atochina-Vasserman, Elena N., Elena Abramova, Melane L. James, Ryan Rue, Amy Y. Liu, Nathan-Tessema Ersumo, Chang-Jiang Guo, Andrew J. Gow, and Vera P. Krymskaya. 2015. “Pharmacological Targeting of VEGFR Signaling with Axitinib Inhibits Tsc2-Null Lesion Growth in the Mouse Model of Lymphangioleiomyomatosis (LAM).” American Journal of Physiology. Lung Cellular and Molecular Physiology, October, ajplung.00262.2015. doi:10.1152/ajplung.00262.2015.

Szpurek, Dariusz, Sebastian Szubert, Pawel Zielinski, Andrzej Frankowski, Stefan Sajdak, and Rafal Moszynski. 2015. “Malignant Presentation of Uterine Lymphangioleiomyomatosis.” Taiwanese Journal of Obstetrics & Gynecology 54 (5): 603–7. doi:10.1016/j.tjog.2015.08.015.

 

Continuing Education Opportunities

The European Respiratory Society (ERS) is offering several courses as continuing medical education. Please visit the ERS website at click here for a list of courses and a description of each.