Applying for LAM Research Funding

The LAM Foundation is the largest funder of LAM research, outside of the National Institutes of Health.  The Foundation has committed over $10 million to LAM research, the majority of which has supported 102 peer-reviewed grants and translational projects.  LAM Foundation-funded scientists reported several major discoveries, including evidence that LAM is genetic, the identification of a LAM gene, and a molecular explanation for abnormal smooth muscle cell growth in LAM.  This data led to the identification of a therapy for LAM called sirolimus, or rapamycin, with clinical trial results published in the April 2011 issue of the New England Journal of Medicine (NEJM).  Several additional molecular targets have been identified, many of which are addressable with drugs that are FDA-approved for other indications.

LAM Foundation research awards include Post-Doctoral Fellowships, Established Investigator Awards, and Pilot Project Awards.  The Foundation also considers proposals for clinical trials, bridge funding, and special projects.  Proposals are peer-reviewed, ranked by the Foundation’s Scientific Advisory Board and voted on by the Board of Directors.  A primary objective of the Foundation’s Research Program is to elevate LAM science to levels that are competitive for more substantial funding from federal sources.

Candidates for LAM Foundation awards must have at least two years of research experience, an MD, PhD or equivalent degree, and perform their work in a laboratory with established expertise in smooth muscle biology, genetics of tuberous sclerosis, or other LAM-related areas.  Investigators of all nationalities are eligible, but candidates must possess visas that allow for completion of the proposed project in the original laboratory.  

Scientists who wish to apply for LAM research funding must submit a Letter of Intent (LOI).  LOIs are reviewed by the Scientific Advisory Board (SAB) for scientific merit and alignment with The LAM Foundation mission.  SAB invitations to submit full proposals are extended to applicants whose LOI proposals are considered competitive, but invitations are not a prerequisite for submission.  Full proposals should be completed online and sent electronically to Judy Sheridan

LAM Foundation Research Funding Deadlines

LOIs must be submitted by July 30, 2013

SAB invitations extended to applicants by August 15, 2013

Full proposals must be submitted by September 30, 2013

Applicants notified by December 15, 2013

Funding begins in January 2014

Application Forms and Additional Research Award Information

Click here for Letter of Intent Form
Click here for Application Form
Click here for Description of Awards
Click here for Terms and Conditions
Click here for LAM Foundation Policy on Indirect Costs

All forms must be completed using the Arial font size 11 and single-line spacing.

To learn more about LAM Foundation research awards contact:

Francis X. McCormack, MD
Chairman, LAM Foundation Scientific Board
Director, Division of Pulmonary Critical Care Medicine
University of Cincinnati Medical Center
Department of Medicine
MSB Room 6053 231 Albert Sabin Way
Cincinnati, OH 45267-0564
P: 513-558-4831
F: 513-558-4858

Other ways to get involved:

Raise awareness of LAM in the scientific community
Encourage other scientists to go to our website to learn more about how to apply for research funding
Write your congressman to promote increased federal funding for research, treatment and educational programming for LAM