• The LAM Foundation awarded $610,000 to fund six new research projects in 2021 including three first-time award recipients.Grant Awardee Information

  1. Seed Grant
     $10,000
     Amy Ryan, Ph D
     University of Iowa
     Interaction of Lymphatic Endothelial and LAM Cells Driving Lymphangioleiomyomatosis Pathogenesis
  2. Pilot Award
     $50,000
     Rhonda Szczesniak, PhD
     Cincinnati Children’s Hospital Medical Center
     Monitoring Risk of Rapid Lung Function Decline: The LAM Prediction (LAMP) Early Translation Study
  3. Special Research Award
     $70,000
     Yan Xu, PhD
     Cincinnati Children’s Hospital Medical Center
     LAM Cell Atlas (LCA): An Intuitive Web Portal for Integrative Analysis and Visualization of LAM Single Cell Multiomics Data
  4. Established Investigator
     $150,000
     Issam Ben-Sahra, PhD
     Northwestern University
     The TSC-mTORC1 Network Controls Bicarbonate Uptake to Support Cell Growth
  5. Established Investigator
     $150,000
     Yan Tang, PhD
     Brigham and Women’s Hospital
     Nanomedicine for Eliminating Rapamycin Tolerant Persister Cells
  6. Career Development
     $180,000
     Minzhe, Guo
     Cincinnati Children's Hospital Medical Center
     An Information Retrieval System for Multiomics Data Integration and LAM Biomarker Discovery

• A $74,000 LAM pilot grant was awarded via the UPenn Orphan Disease Center’s Million Dollar Bike Ride and the LAM Easy Breathers Cycling Team.

• More than 155 attendees participated in the 2021 Virtual International TSC & LAM Research Conference: Driving Discoveries Beyond Boundaries, co-hosted with the TSC Alliance.

• More than 85 attendees participated in the 2021 LAM Research Virtual Conference, Transforming Our Understanding of LAM: The Path Forward.

• The Foundation conducted an outreach program to support clinical trial recruitment for the MILED trial, which is now 91% enrolled, and contributed $40,000 to sustain the MIDAS registry.

• The LAM Clinic Network provided leadership and guidance during the COVID-19 pandemic to ensure LAM patients had the most up to date resources, including community Q&A webpage, vaccine recommendations, and mask guidelines. The Foundation co-hosted 2 virtual town halls in partnership with the TSC Alliance, which received over 675 viewings.
• The LAM Foundation hosted quarterly LAM Clinic Director meetings to facilitate clinical trial updates, rare lung diseases case study presentations and roll-out of new of tools for patient support via the LAM Clinic Network.
• The LAM Foundation was awarded a $15,000 Community Service Grant from CHEST for the dissemination of the LAM Clinical Practice Guidelines around the world.

• Over 200 individuals registered with the Foundation: 100+ from the United States and nearly 100 from other countries.
• In collaboration with our LAM clinic directors, liaisons, and scientists we offered 25 virtual events, including LAMposium in Your Living Room webinars, educational meetings, and social gatherings.
• More than 1,100 members of our global community attended our virtual events, and the recorded presentations received over 650 viewings, further spreading LAM education and awareness around the globe.
• Three Circle of Hope Transplant Support Program participants received a lung transplant this year, resulting in the donation of more than 10 tissue samples to further LAM research.

The LAM Foundation publishes its IRS Form 990, Functional Expenses and Audited Financial Statements on the About Us page of the website.