Grant Opportunities


Letter of Intent

The first step in the process of a grant application to The LAM Foundation is to submit a Letter of Intent (LOI). The submission of an LOI is required for each grant category. An applicant must submit an LOI in order to submit a grant application.

Application Timeline for In-Cycle Grants

With the exception of Travel Grants, The LAM Foundation requires all applicants to submit their LOI using the online application form available at our grant website (proposalCENTRAL).

Note: Applicants must create a profile and be logged in to proposalCENTRAL in order to access The LAM Foundation’s LOI Form. To aid applicants in navigating our online grant system, we offer a step-by-step tutorial by clicking here.

Inquiries or technical issues regarding proposalCENTRAL and the online application process should be directed to their customer support:
Toll Free Phone: 800-875-2562 option #2

Collaboration with Tuberous Sclerosis Alliance in Research Funding

The LAM Foundation has historically collaborated with the Tuberous Sclerosis Alliance to fund projects that fulfill the research mission of both organizations. You will be asked if you have or will be submitting your project to the Tuberous Sclerosis Alliance for funding in this grant cycle.

Grant Application

If your LOI is approved, The LAM Foundation will invite you to submit a full grant application. Click the following link for information and instructions regarding the submission of a grant application.

For information about The LAM Foundation’s in-cycle grant application process or requirements, please contact Judy Sheridan, Grant and Research Manager at


In-Cycle Research Grant Categories:


Pilot and Feasibility Grantplus

Funding Level: Maximum of $50,000 may be requested.
Period: Up to 1 year of support is available.

The objective of this grant is to provide funds to encourage the development and testing of new hypotheses and/or new methods in research areas relevant to LAM. Proposed work must be hypothesis generating or hypothesis testing, reflecting innovative approaches to important questions in LAM research or development of novel methods, and providing sufficient preliminary data to justify the Foundation’s support. Results from Pilot and Feasibility Grants should lead to the submission of applications for funding from other agencies (i.e. NIH). At the conclusion of the funding term, applicants are expected to apply for further funding by other mechanisms or from outside agencies. The award is not intended to support continuation of programs begun under other granting mechanisms.

Career Development Research Grantplus

Funding Level: A maximum of $60,000 per year may be requested.
Period: Up to 3 years of support is available. Any funds remaining at the end of each year must be returned to the Foundation unless outlined in your originally submitted project budget or given prior approval.

The objective of this grant is to provide support for postdoctoral research fellows who are starting their research careers and are working in the laboratories of established researchers or conducting research with the mentorship of established researchers. In addition, this grant category is intended to provide support for postdoctoral research fellows or investigators with less than three years in a faculty position who intend to pursue a career in LAM research. Applications will be accepted from candidates holding an M.D., Ph.D. or equivalent degrees who are interested in conducting basic science, clinical research related to LAM. Applicants must indicate a commitment to LAM-related research by focusing 50% of their time on LAM in research or clinical practice. More than 50% of the funds must be used for salary support. The balance of the funds may be used for fringe benefits, supplies, or animal costs. No overhead or indirect costs are provided.

Established Investigator Research Grantplus

Funding Level: Maximum of $50,000 per year may be requested.
Period: Up to 3 years. This award may be condensed to two years should the investigator request it. Any funds remaining at the end of each year must be returned to the Foundation unless outlined in your originally submitted project budget or given prior approval.

The objective of this grant is to provide funds to faculty level investigators for technician support and supplies to encourage the development of new information that contributes to the understanding of the basic biology of LAM expression, and the pathogenesis/management of LAM. In addition, consideration will be given to those projects that provide insight into the development of information that may contribute to new therapies for LAM. All proposals must be hypothesis generating or hypothesis testing and provide sufficient preliminary data to justify The LAM Foundation’s support.

Travel Grantplus

Funding Level: $1,000

The LAM Foundation sends out a “Call for Abstracts” prior to certain LAM International Research Conferences. Abstracts will be reviewed by the conference organizers and members of the Scientific Advisory Board. Platform Presentations will be selected from submitted abstracts based on scientific merit and thematic considerations. A travel grant will be awarded to those selected as Platform Presenters. Notification of acceptance and selection for presentation will be issued to the submitting author via email. This will provide time for presenters to register for the conference and allow travel grant awardees to make airline reservations at least 3 weeks in advance.






The LAM Foundation also considers proposals for clinical trials, bridge funding and other special projects.

Please contact The LAM Foundation at for information about the Foundation's out-of-cycle grant opportunities.

UPENN Orphan Disease Center Million Dollar Bike Ride Grantplus

2017 Million Dollar Bike Ride Pilot Grant Program

The Orphan Disease Center (ODC) at the University of Pennsylvania invites you to participate in the 2017 Million Dollar Bike Ride Pilot Grant Program. The program is now open and offering 33 different research grant opportunities focusing on 23 different rare diseases. The LAM Foundation and Easy Breathers Cycling Team were represented in the 2017 Million Dollar Bike Ride and raised money to fund two $50,600 Pilot Grants for LAM research. This RFA is open to the international community. All individuals holding a faculty‐level appointment at an academic institution or a senior scientific position at a non-profit institution or foundation are eligible to respond to this RFA.

For more details about this grant program, rare disease focus areas and how to apply, please visit the ODC website. Letters of Interest (LOIs) are due no later than Monday, September 18, 2017 by 8pm EST. Please refer to PENN Medicine Orphan Disease Center website for instructions on LOI submission.

Please contact:
Samantha Charleston
Assistant Director
Orphan Disease Center
University of Pennsylvania
Phone: 215-573-6822